I had a friend in high school, Matt, who was the lucky one in our little rockhead guitar circle - while we were all playing budget-oriented guitars, his Dad bought him the first Kramer Baretta that hit our small market. It was an original full non-tilt paddlehead Baretta in creme with a real Floyd Rose (another seemingly unobtainium at that time), exactly like the one EVH had in the "No Bozos" ad that today is one of the holy grail for shredder collectors. It was the only of its type to ever hit our market, the next round were the tilt-head smaller paddles that were the production line guitars.
Matt's Mom (a "cat lady" in the true sense) had several cats that ran their home and a few of them adopted the guitar's case at the time as a litterbox one weekend. It smelt HORRID, I can't begin to describe how bad it smelt, I mean sicken your stomach bad. We discovered the weekend mess and tried to clean, air out, Febreeze, everything, to no avail - it was never the same. Matt got in a cramp and used it one time to carry the guitar to a "gig" (house party with throw-together band) and the guitar itself instantly took on the same smell. The guitar went from being our envy and our hands-on at every possible opportunity to being a discarded outcast.
Since the case was now a leper and the cats liked, it, Matt's cat lady mom adopted it for her babies as their permanent litter box in that room (every room of the house had litter boxes, some formal, some "created"). Outside of the odor, the case eventually started separating at all seams and had to be thrown away because it couldn't even serve as a litter box anymore. That was one of the old split-headstock lower-case logo Kramer branded cases - it alone would be worth prime money today.
And I never saw the guitar after we all went to our colleges, but Matt told me years later he ended up refinning the Baretta (himself, rattlecan) primarily because of the odor. He sold it shortly thereafter, for a literal fraction of what it was worth then, let alone what it would be worth now.