That actually was the case for me too when I developed some hand issues around 2012. I did work past the issue.
Around 2023, I developed new hand issues. I’m still trying to work through them, but for now it’s thin necks that provide comfort.
Funny how that goes.
As to string gauges, I’m down from 11s to 9s on 25.5, and 10s on 34.75. I adapted fairly quickly, but I did come from the land of 9s prior to going with 11s. This is also due to hand issues, and it’s been helpful.